This study investigated counselling interventions through work benefits and its effects on career choice among Technical Secondary Schools in the South West Region of Cameroon. This study was predicated on the understanding that technical secondary school students face numerous challenges when making a career choice earlier in the academic ladder, necessitating specific intervention to enhance a stable career choice. The objective was to investigate the extent to which orientation on work benefits affects students’ career choice in Technical Secondary Schools. Methodologically, the study employed a mixed-method approach with a quasi-experimental design, encompassing both quantitative and qualitative elements. The research sample comprised 20 students and 45 guidance counselors selected from the South West Region of Cameroon, with selection criteria based on document analysis for students and the Division with the highest number of guidance counselors. Data collection was facilitated through questionnaires, and the analysis incorporated both descriptive and inferential statistical methods. The Likelihood ratio test was used in testing the hypotheses from data collected from the guidance counselors. An Independent Sample T-test was also used to compare how students in both the control and experimental groups at the pretest and post-test levels differ in their mean scores. The qualitative data derived from open-ended questions were analyzed using a thematic analysis approach, with the aid of identified themes. The research revealed a remarkably strong correlation between an individual’s orientation toward work benefits and their ultimate career choices. This relationship was substantiated by an overwhelming 90.8% consensus among guidance counselors and further validated by a robust contingency value of 0.835 on a scale of 0 to 1, demonstrating statistical significance with a p-value of 0.000< 0.05. Based on these compelling results, the researchers proposed several actionable recommendations for guidance counselors. It was recommended that career educators pay close attention to training students on practical exercises for evaluating work benefits. Also, schools and educational policymakers prioritize the integration of work benefits orientation into career guidance programs, ensuring that students are equipped with the knowledge to make well-informed and sustainable career choices. These recommendations reflect a holistic approach to career guidance that acknowledges the crucial role of sustained engagement and practical experience in shaping effective career choices